Most modern biological assays work on the principle of introducing an exogenous label into a native biological system so that it can be detected as a signal to aid in the measurement of a specific aspect of the concerned biological system. Ideally, it is desirable to input minimum external agents into the biological system under study.
According to the report “Europe Label Free Detection Market By Technology (Bio-layer Interferometry, Cellular Dielectric Spectroscopy, Optical Waveguide Grating Technology, Surface Plasmon Resonance), By Product Type (Consumables Such As Biosensor Chips And Microplates, Instruments), By Application (Binding Kinetics, Binding Thermodynamics, Endogenous Receptor Detection, Hit Confirmation, Lead Generation), And By Region - Industry Analysis, Size, Share, Growth, Trends, And Forecasts (2016–2021)” report by Market Data Forecast, the Europe Label Free Detection Market was worth USD 330 million in 2016 and estimated to be growing at a CAGR of 11.17%, to reach USD 440 million by 2021.
Label-free systems have been introduced in hopes of fulfilling this requirement.
The progress made by the label free detection market can be seen not only through the sales figures that speak for themselves, but they have also ushered in a new era of drug development.
The prominent features of Label Free Detection involve scientists being able to study primary cell types along with the endogenous receptors in cell lines. Both grant access to receptors in several natural states.
The data gathered from Label Free Detection technologies is albeit a bit complex but provides a better reflection of the target biology. Recent advances in the label free instruments industry offer improved cost, efficiency, higher levels of sensitivity as well as sophisticated data analysis.
The advantage of the implementation of label free technologies is that a plethora of cells can be used as targets for analysis. The cells aren’t genetically manipulated in any way while they perform their metabolic processes as any radioactive or fluorescent marker is absent in this mode of detection.
This ensures that the response recorded by the researcher is as authentic as it can get as the cell’s physiological activity is uncontaminated. Other advantages of label free technologies include decreased costs, decreased instrument sizes as well as higher value for money capital.
As for the constraints of using label free technologies, it is often regarded as a ‘black box’ technology, wherein the user finds it difficult to decode the signals. Also in the medical field, each customer is unique.
LFD technology finds it difficult to understand the customers’ needs.
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The Europe Label Free Detection market is broadly classified into Consumables (Biosensor Chips and Microplates) and Instruments based on product type. Furthermore, based on application they are classified into Binding Kinetics, Binding Thermodynamics, Endogenous Receptor Detection, Hit Confirmation and Lead Generation.
Based on technology used, they are classified into Bio-layer Interferometry(BLI), Cellular Dielectric Spectroscopy, Optical Waveguide Grating Technology(OWG) and Surface Plasmon Resonance(SPR). Based on geography, the Europe market is divided mainly into Germany, France, U.K, Italy and Spain.
The Europe market boasts the second highest market share with around 25% in addition to having a CAGR of 11.17% which is just under the global CAGR rate.
Some of the major companies dominating the market, by their products and services include Attana AB and Roche based in Switzerland. In addition to this Ametek, Inc., Bio-Rad Laboratories, Inc., BiOptix, Corning, Inc., Danaher Corporation, General Electric Corporation, Pall Corporation, PerkinElmer, all companies based in U.S, have a global presence and extend their services to the European market as well.
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