NAD Dependent Protein Deacetylase Sirtuin 1 - Pipeline Review, H2 2017, outlays comprehensive information on the NAD Dependent Protein Deacetylase Sirtuin 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
NAD Dependent Protein Deacetylase Sirtuin 1 (SIR2 Like Protein 1 or Sirtuin Type 1 or Regulatory Protein SIR2 Homolog 1 or SIRT1 or EC 3.5.1.) - NAD-dependent deacetylase sirtuin-1 is a protein encoded by the SIRT1 gene. It modulates chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.
It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).
Complete Report Available at www.themarketreports.com/report/na…e-review-h2-2017
- The report provides a snapshot of the global therapeutic landscape for NAD Dependent Protein Deacetylase Sirtuin 1
- The report reviews NAD Dependent Protein Deacetylase Sirtuin 1 targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in NAD Dependent Protein Deacetylase Sirtuin 1 targeted therapeutics and enlists all their major and minor projects
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- Develop strategic initiatives by understanding the focus areas of leading companies
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- Devise corrective measures for pipeline projects by understanding NAD Dependent Protein Deacetylase Sirtuin 1 development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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