'Transforming Growth Factor Beta 1- Pipeline Review, H2 2017' outlays comprehensive information on the Transforming Growth Factor Beta 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.
Transforming Growth Factor Beta 1 (TGFB1) - Transforming growth factor beta 1 (TGF-β1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines encoded by the TGFB1 gene. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
It promotes either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. It leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression at high concentration.
It leads to expression of the IL-17 and IL-23 receptors favoring differentiation to Th17 cells at low concentration.
Complete Report Available at www.themarketreports.com/report/tr…ne-review-h2-2017
Reasons to access
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Transforming Growth Factor Beta 1 (TGFB1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
Access this Report at www.themarketreports.com/report/941433
- Acceleron Pharma Inc
- Eli Lilly and Co
- Ensol Biosciences Inc
- Formation Biologics Inc
- Genzyme Corp
- Huabo Biopharm Co Ltd
- Isarna Therapeutics GmbH
- Johnson & Johnson
- Novartis AG
- Scholar Rock Inc
- Sirnaomics Inc
Inquire About this Report at www.themarketreports.com/report/ask-your-query/941433
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