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Learn details of the transforming growth factor beta 1 (tgfb1) pipeline report

Industrial Market Research

'Transforming Growth Factor Beta 1- Pipeline Review, H2 2017' outlays comprehensive information on the Transforming Growth Factor Beta 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

Transforming Growth Factor Beta 1 (TGFB1) - Transforming growth factor beta 1 (TGF-β1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines encoded by the TGFB1 gene. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

It promotes either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. It leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression at high concentration.

It leads to expression of the IL-17 and IL-23 receptors favoring differentiation to Th17 cells at low concentration.

Complete Report Available at…ne-review-h2-2017

Reasons to access

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Transforming Growth Factor Beta 1 (TGFB1)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics

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Companies Mentioned

  • Acceleron Pharma Inc
  • Eli Lilly and Co
  • Ensol Biosciences Inc
  • Formation Biologics Inc
  • Genzyme Corp
  • Huabo Biopharm Co Ltd
  • Isarna Therapeutics GmbH
  • Johnson & Johnson
  • Novartis AG
  • Scholar Rock Inc
  • Sirnaomics Inc

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