E3 Ubiquitin Protein Ligase Mdm2 - Pipeline Review, H2 2017, outlays comprehensive information on the E3 Ubiquitin Protein Ligase Mdm2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
E3 Ubiquitin Protein Ligase Mdm2 (Double Minute 2 Protein or Hdm2 or Oncoprotein Mdm2 or p53 Binding Protein Mdm2 or MDM2 or EC 6.3.2.) - E3 ubiquitin-protein ligase Mdm2 is a protein encoded by the MDM2 gene. It acts as an ubiquitin ligase E3 toward itself and ARRB1.
It permits the nuclear export of p53/TP53. It promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.
It inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation.
The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 3, 3, 7 and 4 respectively.
Complete Report Available at www.themarketreports.com/report/e3…ne-review-h2-2017
Reasons to access
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for E3 Ubiquitin Protein Ligase Mdm2
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
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List of Figures
- Number of Products under Development by Stage of Development, H2 2017
- Number of Products under Development by Therapy Areas, H2 2017
- Number of Products under Development by Top 10 Indications, H2 2017
- Number of Products by Stage and Mechanism of Actions, H2 2017
- Number of Products by Routes of Administration, H2 2017
- Number of Products by Stage and Routes of Administration, H2 2017
- Number of Products by Molecule Types, H2 2017
- Number of Products by Stage and Molecule Types, H2 2017
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