Learn details of the Global Trends, opportunities, Competitive Landscape and Forecasts Analysis 2020. This research report provides detailed country analysis of The United States and Europe.
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This report provides a wide-ranging study of global Wilson's disease market and also its key regional markets such as the US and Europe. Furthermore, market dynamics such as key trends and development; and challenges are analyzed in depth.
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The global Wilson's disease industry is highly competitive consisting of several large corporations.
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Wilson's disease is a rare disease and is named after Kinnear Wilson who was the first to describe this disorder in 1912. His description terms the disease as a progressive lenticular degeneration, a hereditary, fatal neurological disease that is usually accompanied by chronic liver ailment that leads to a condition called cirrhosis.
Wilson's disease is a hereditary disorder that leads to unwarranted accumulation of copper in crucial organs such as the liver, brain. The patient starts to accumulate copper from birth but diagnosis tends not to occur only in the later ages.
The primary signs of Wilson's disease become prominent usually between the ages of 12 and 23 years.
Wilson's disease is caused by the mutation of a gene named ATP7B. Absent or reduced function of ATP7B protein leads to reduced elimination of copper into the bile.
Wilson's disease is inherited as an autosomal recessive trait, which means that in order to develop the disease one must inherit two procreations of the defective gene, one from each parent. If a person receives only one abnormal gene from either of the parents, he/she is not likely to get affected by the Wilson's disease.
Wilson's disease may be difficult to primarily diagnose as the symptoms are alike to other health issues like heavy metal poisoning, hepatitis C, and cerebral palsy.
The important factors that are anticipated to drive the Wilson's disease market include rising prices of chelators in the US, rising attractiveness of orphan drugs market, increasing global healthcare expenditure as well as spending on medicines. The noteworthy trends in the market include falling number of prescriptions for Wilson's disease, and the development of gene therapy as a potential cure for the disease.
However, the market is confronted by crucial challenges such as under-diagnosis of the disease, lack of safety in treatments, poor compliance to current treatments and unmet efficacy needs.
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